Guanosine

Guanosine

SCHEMBL531207

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.76
HINT1 P49773 4/20 0.68
NT5E P21589 2/20 0.68
PNP P00491 1/20 0.65
PAX8 Q06710 1/20 0.65
GSK3A P49840 2/20 0.64
RPS6KA3 P51812 2/20 0.64
MAPK14 Q16539 2/20 0.64
TGM2 P21980 1/20 0.62
LMNA P02545 1/20 0.62
HIF1A Q16665 1/20 0.62
ADORA2A P29274 3/20 0.62
ADORA3 P0DMS8 1/20 0.62
ADORA2B P29275 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL34912 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL8593215 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL413586 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049416 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL11986902 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049608 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049417 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049467 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL20750695 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL16800938 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106047872-A DNA aptamer sequences for recognizing bentazone and derivatives thereof 清华大学 2016-10-26 CN claimed
US-20130183765-A1 Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy Sena Research Incorporated (US) 2013-07-18 US claimed
EP-3795574-A1 SYNTHESIS AND USAGE OF 1,2-DIAMINODIAMANTANE PLATINUM(II) COMPLEXES Justus-Liebig-Universität Gießen (DE) 2021-03-24 EP disclosed
CN-110292163-A A kind of constant temperature refined honey method 浙江中医药大学 2019-10-01 CN disclosed
CN-110184209-A One plant of Lactobacillus rhamnosus that can reduce blood uric acid 杭州娃哈哈科技有限公司 2019-08-30 CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
US-20190003966-A1 Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy SENA RESEARCH, INCORPORATED (US) 2019-01-03 US disclosed
US-10073033-B2 Ultraviolet and high-performance liquid chromatography methods for the evaluation of sunscreen efficacy SENA RESEARCH, INC. (US) 2018-09-11 US disclosed
CN-106635799-A Screening method of guanosine production bacterial strains 广东肇庆星湖生物科技股份有限公司 2017-05-10 CN disclosed
CN-102924551-B A kind of method extracting guanosine from fermented liquid TONGLIAO MEIHUA BIOTECHNOLOGY CO., LTD. (CN) 2016-02-24 CN disclosed
CN-101974432-B High-throughput screening method of guanosine production strains STAR LAKE BIOSCIENCE CO INC ZHAOQING GUANGDONG 2015-06-17 CN disclosed
CN-101633781-A Emulsion composition, method for softening fiber structure and fiber containing base material DOWCORNING SHANGHAI CO LTD 2010-01-27 CN disclosed
CN-101492484-A Synthetic circulation production process for guanine nucleoside HUNAN SECO BIOTECHNOLOGY CO LT (CN) 2009-07-29 CN disclosed
CN-101487036-A Production method of guanine nucleosides HUNAN SECO CO LTD (CN) 2009-07-22 CN disclosed
CN-1910192-A Metal complexes having vitamin B12 as a ligand UNIV ZUERICH (CH) 2007-02-07 CN disclosed
CN-1864697-A Application of non-adenine in preparation of drug for promoting wound healing WEIHAI MAPLE LEAF TECHNOLOGY D (CN) 2006-11-22 CN disclosed
EP-1720568-A2 IMMUNOSTIMULATORY VIRAL RNA OLIGONUCLEOTIDES Coley Pharmaceutical Group, Inc. (US) 2006-11-15 EP disclosed
US-20050256073-A1 Immunostimulatory viral RNA oligonucleotides COLEY PHARMACEUTICAL GROUP, INC. (US) 2005-11-17 US disclosed
WO-2005097993-A2 IMMUNOSTIMULATORY VIRAL RNA OLIGONUCLEOTIDES COLEY PHARMACEUTICAL GROUP, INC. (US) 2005-10-20 WO disclosed
US-4816447-A HERPES VIRUS MERCK & CO., INC. (US) 1989-03-28 US disclosed