Guanosine

Guanosine

SCHEMBL34912

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.76
HINT1 P49773 4/20 0.68
NT5E P21589 2/20 0.68
PNP P00491 1/20 0.65
PAX8 Q06710 1/20 0.65
GSK3A P49840 2/20 0.64
RPS6KA3 P51812 2/20 0.64
MAPK14 Q16539 2/20 0.64
TGM2 P21980 1/20 0.62
LMNA P02545 1/20 0.62
HIF1A Q16665 1/20 0.62
ADORA2A P29274 3/20 0.62
ADORA3 P0DMS8 1/20 0.62
ADORA2B P29275 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL8593215 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL531207 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL413586 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049416 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL11986902 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049608 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049417 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL24049467 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL20750695 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8
Guanosine SCHEMBL16800938 1.00 HPGD (0.76) HPGDHINT1NT5EPNPPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1951 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120060108-A Method for high-yield phenazine-1-carboxamide by utilizing pseudomonas 齐鲁工业大学(山东省科学院) 2025-05-30 CN claimed
US-20250171815-A1 PRODUCTION OF PSYCHEDELIC COMPOUNDS CORE ONE LABS INC (CA) 2025-05-29 US claimed
WO-2025090773-A1 ASSESSMENT OF SYSTEMIC IMMUNITY USING [F18]F-Ara-G IN POSITRON EMISSION TOMOGRAPHY CELLSIGHT TECHNOLOGIES INC. (US) 2025-05-01 WO claimed
US-12157766-B2 Cytoplasmic expression system Absci Corporation (US) 2024-12-03 US claimed
EP-4463556-A1 PRODUCTION OF PSYCHEDELIC COMPOUNDS Core One Labs Inc. (CA) 2024-11-20 EP claimed
CN-117778499-A Method for producing arabinonucleoside by biocatalysis 河南师范大学 2024-03-29 CN claimed
EP-4273257-A2 INDUCIBLE COEXPRESSION SYSTEM ABSCI Corporation (US) 2023-11-08 EP claimed
CN-116479075-A Method for preparing arabinoside through enzyme catalysis 河南师范大学 2023-07-25 CN claimed
WO-2023130191-A1 PRODUCTION OF PSYCHEDELIC COMPOUNDS CORE ONE LABS INC. (CA) 2023-07-13 WO claimed
CN-116298235-A Serum metabolism biomarker for diagnosing or monitoring breast cancer and screening method thereof 哈尔滨医科大学 2023-06-23 CN claimed
EP-1283874-A2 NOVEL DEOXYNUCLEOSIDE KINASE ENZYME VARIANTS Knecht, Wolfgang (DK) 2003-02-19 EP claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
US-20020052345-A1 Novel prodrugs for phosphorus-containing compounds METABASIS THERAPEUTICS, INC. 2002-05-02 US claimed
EP-1165570-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS Metabasis Therapeutics, Inc. (US) 2002-01-02 EP claimed
WO-2001088106-A2 NOVEL DEOXYRIBONUCLESIDE KINASE ENZYME MULTI-SUBSTRATE VARIANTS KNECHT WOLFGANG (DK) 2001-11-22 WO claimed
US-6312662-B1 CONVERSION BY HUMAN LIVER MICROSOMES TO MPO3H2 METABASIS THERAPEUTICS, INC. 2001-11-06 US claimed
WO-2000052015-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS, INC. (US) 2000-09-08 WO claimed
EP-0549615-A4 SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION ISIS PHARMACEUTICALS INC (US) 1997-08-27 EP claimed
EP-0549615-A1 SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1993-07-07 EP claimed
WO-1992003568-A1 SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1992-03-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052345-A1 Novel prodrugs for phosphorus-containing compounds CCRL2, CCR4, ALK HPGD 3661/4885HINT1 2929/4885NT5E 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.