Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306763 | 0.92 | HPGD (0.35) | APOBEC3AAPOBEC3GNTRK1HPGDALDH1A1 | |
| SCHEMBL5306949 | 0.91 | APOBEC3A (0.38) | APOBEC3AAPOBEC3GHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5311331 | 0.90 | MAPT (0.34) | APOBEC3AAPOBEC3GNTRK1HPGDALDH1A1 | |
| SCHEMBL5312693 | 0.89 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GNTRK1HPGDALDH1A1 | |
| SCHEMBL5309593 | 0.89 | HPGD (0.39) | APOBEC3AAPOBEC3GHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5306834 | 0.88 | PDE4A (0.37) | APOBEC3AAPOBEC3GNTRK1HPGDALDH1A1 | |
| SCHEMBL5311722 | 0.87 | HPGD (0.34) | APOBEC3AAPOBEC3GHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5313987 | 0.87 | HPGD (0.34) | APOBEC3AAPOBEC3GHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5309825 | 0.87 | IRAK4 (0.36) | APOBEC3AAPOBEC3GNTRK1HPGDALDH1A1 | |
| SCHEMBL5309338 | 0.86 | IRAK4 (0.38) | APOBEC3AAPOBEC3GALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |