Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306834 | 0.93 | PDE4A (0.37) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5309338 | 0.92 | IRAK4 (0.38) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5312693 | 0.92 | APOBEC3A (0.35) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5310044 | 0.92 | MEN1 (0.39) | TP53MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5306763 | 0.91 | HPGD (0.35) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5370148 | 0.90 | TP53 (0.44) | HPGDKDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL5311722 | 0.90 | HPGD (0.34) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5313987 | 0.90 | HPGD (0.34) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL5310626 | 0.89 | ALKBH5 (0.36) | APOBEC3AAPOBEC3GALKBH5 | |
| SCHEMBL5312653 | 0.89 | APOBEC3A (0.35) | HPGDKDM4ELMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |