Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766834 | 0.83 | MCHR1 (0.49) | MCHR1KCNH2MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL4129888 | 0.83 | MCHR1 (0.48) | MCHR1KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL5312483 | 0.79 | MCHR1 (0.50) | MCHR1KCNH2MEN1KMT2A | |
| SCHEMBL4763144 | 0.75 | DNMT3A (0.46) | MCHR1MEN1KMT2AHRH3 | |
| SCHEMBL4724745 | 0.75 | DNMT3A (0.44) | MCHR1KCNH2MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL4118824 | 0.74 | DNMT3A (0.45) | MCHR1MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL4124308 | 0.74 | DNMT3A (0.43) | MCHR1KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL5307093 | 0.74 | L3MBTL3 (0.53) | MCHR1KCNH2 | |
| SCHEMBL5307466 | 0.74 | DNMT3A (0.62) | MCHR1MEN1KMT2A | |
| SCHEMBL4723726 | 0.73 | ACHE (0.47) | MCHR1KCNH2MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042668-A1 | DERIVATIVES OF 1-AMINO-ISOQUINOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS IN THE TREATMENT OF A DYSFUNCTION ASSOCIATED WITH MCH RECEPTOR 1 | SANOFI-AVENTIS (FR) | 2007-04-19 | — | — | WO | claimed |
| WO-2007042668-A1 | DERIVATIVES OF 1-AMINO-ISOQUINOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS IN THE TREATMENT OF A DYSFUNCTION ASSOCIATED WITH MCH RECEPTOR 1 | SANOFI-AVENTIS (FR) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007042668-A1 | DERIVATIVES OF 1-AMINO-ISOQUINOLINE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS IN THE TREATMENT OF A DYSFUNCTION ASSOCIATED WITH MCH RECEPTOR 1 | SANOFI-AVENTIS (FR) | 2007-04-19 | — | — | WO | disclosed |