Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 6/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315698 | 0.91 | LCK (0.38) | LCKTYK2IRAK4MEN1KMT2A | |
| SCHEMBL14531398 | 0.88 | LCK (0.41) | LCKTYK2IRAK4MEN1KMT2A | |
| SCHEMBL5312793 | 0.85 | LCK (0.38) | LCKIRAK4MEN1KMT2AKDM4E | |
| SCHEMBL5312683 | 0.81 | LCK (0.39) | LCKTYK2IRAK4ALDH1A1CA12 | |
| SCHEMBL5315254 | 0.80 | MAPT (0.42) | LCKMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5313953 | 0.79 | KDR (0.51) | LCKIRAK4 | |
| SCHEMBL5314211 | 0.78 | HDAC1 (0.41) | LCKTYK2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5314681 | 0.75 | LCK (0.41) | LCK | |
| SCHEMBL12482903 | 0.72 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL5315703 | 0.72 | LCK (0.40) | LCKTYK2IRAK4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |