Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312793 | 0.94 | LCK (0.38) | LCKIRAK4EGFRROCK2CSNK1D | |
| SCHEMBL5312781 | 0.91 | LCK (0.39) | LCKIRAK4TYK2HSD17B10MAPT | |
| SCHEMBL5315703 | 0.81 | LCK (0.40) | LCKIRAK4TYK2ROCK2CSNK1D | |
| SCHEMBL5314681 | 0.81 | LCK (0.41) | LCKROCK2 | |
| SCHEMBL14531398 | 0.80 | LCK (0.41) | LCKIRAK4TYK2ROCK2RAF1 | |
| SCHEMBL5313953 | 0.79 | KDR (0.51) | LCKIRAK4ROCK2 | |
| SCHEMBL5314747 | 0.78 | LCK (0.49) | LCKROCK2ALDH1A1 | |
| SCHEMBL5314803 | 0.77 | LCK (0.40) | LCKROCK2CSNK1DMAPTMEN1 | |
| SCHEMBL5315254 | 0.77 | MAPT (0.42) | LCKHSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL5314211 | 0.76 | HDAC1 (0.41) | LCKTYK2ROCK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |