Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313953 | 0.89 | KDR (0.51) | LCKKDRROCK2GRK2 | |
| SCHEMBL14530688 | 0.88 | LCK (0.42) | LCKLIPGEPHB4ALDH1A1TYK2 | |
| SCHEMBL5315254 | 0.87 | MAPT (0.42) | LCKKDRALDH1A1CYP1A2HPGD | |
| SCHEMBL5314803 | 0.82 | LCK (0.40) | HDAC1HDAC8HDAC6LCKKDR | |
| SCHEMBL5314747 | 0.82 | LCK (0.49) | LCKKDRALDH1A1ROCK2GRK2 | |
| SCHEMBL5314220 | 0.82 | LCK (0.41) | LCKKDRLIPGEPHB4TYK2 | |
| SCHEMBL5314681 | 0.80 | LCK (0.41) | LCKKDRROCK2GRK2 | |
| SCHEMBL5312781 | 0.78 | LCK (0.39) | LCKALDH1A1HPGDSMN1; SMN2TYK2 | |
| SCHEMBL5315698 | 0.76 | LCK (0.38) | LCKALDH1A1HPGDTYK2ROCK2 | |
| SCHEMBL5316017 | 0.74 | KDR (0.51) | LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |