Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.35 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312854 | 1.00 | PDE10A (0.41) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5312851 | 0.92 | PLA2G2A (0.41) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5312846 | 0.92 | PLA2G2A (0.41) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5309702 | 0.91 | PDE10A (0.43) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5309698 | 0.91 | PDE10A (0.43) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5312224 | 0.84 | PLA2G2A (0.42) | PDE10AKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5312222 | 0.84 | PLA2G2A (0.42) | PDE10AKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5316174 | 0.83 | PPARG (0.40) | PDE10ADHODHKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5312998 | 0.81 | PLA2G4B (0.42) | SMN1; SMN2PPARDCYP2C9CSGALNACT1TP53 | |
| SCHEMBL5312997 | 0.81 | PLA2G4B (0.42) | SMN1; SMN2PPARDCYP2C9CSGALNACT1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |