Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307080 | 0.91 | SCD (0.40) | SCDHCRTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL5309933 | 0.88 | GABRA5 (0.38) | SCDGABRA5KDM4EALDH1A1NPC1 | |
| SCHEMBL5312273 | 0.84 | KCNQ3 (0.44) | SCDKDM4EALDH1A1RAB9A | |
| SCHEMBL5312872 | 0.83 | SCD (0.49) | SCDHCRTR1HCRTR2KDM4ERAB9A | |
| SCHEMBL5311282 | 0.82 | SCD (0.38) | SCDHCRTR1HCRTR2GABRA5NPC1 | |
| SCHEMBL5306881 | 0.79 | SCD (0.51) | SCD | |
| SCHEMBL5309408 | 0.79 | SCD (0.47) | SCD | |
| SCHEMBL5311277 | 0.77 | SCD (0.41) | SCDHCRTR1HCRTR2GABRA5EGLN1 | |
| SCHEMBL5307096 | 0.77 | SCD (0.53) | SCD | |
| SCHEMBL5308879 | 0.77 | SCD (0.56) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |