Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309041 | 0.90 | SCD (0.50) | SCDMAPK8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5312895 | 0.84 | SCD (0.36) | SCDMAPK8KMT2A | |
| SCHEMBL5315119 | 0.84 | SCD (0.44) | SCDALDH1A1SMN1; SMN2HPGDFASN | |
| SCHEMBL5310026 | 0.83 | MAPK8 (0.36) | SCDMAPK8 | |
| SCHEMBL5312062 | 0.82 | SCD (0.49) | SCDALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL5310725 | 0.81 | SCD (0.41) | SCDMAPK8KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5306364 | 0.80 | SCD (0.45) | SCDMAPK8KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5310028 | 0.78 | EGLN1 (0.37) | SCDMAPK8 | |
| SCHEMBL5308998 | 0.76 | SCD (0.51) | SCDMAPK8 | |
| SCHEMBL5309044 | 0.75 | SCD (0.44) | SCDALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |