Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309044 | 0.91 | SCD (0.44) | SCDIRAK4P2RX7 | |
| SCHEMBL5315122 | 0.84 | SCD (0.39) | SCDP2RX7GABRA5EGLN1CYP2C9 | |
| SCHEMBL5312893 | 0.84 | SCD (0.41) | SCDKMT2AMAPK8 | |
| SCHEMBL5310028 | 0.83 | EGLN1 (0.37) | SCDIRAK4CXCR3TRPA1P2RX7 | |
| SCHEMBL5312064 | 0.82 | SCD (0.43) | SCDP2RX7HDAC1HDAC6 | |
| SCHEMBL5306365 | 0.80 | SCD (0.40) | SCDCXCR3P2RX7GABRA5KMT2A | |
| SCHEMBL5310026 | 0.78 | MAPK8 (0.36) | SCDIRAK4CXCR3TRPA1P2RX7 | |
| SCHEMBL5309001 | 0.77 | SCD (0.45) | SCDCXCR3P2RX7 | |
| SCHEMBL5309933 | 0.75 | GABRA5 (0.38) | SCDGABRA5EGLN1MAPK8 | |
| SCHEMBL5309041 | 0.74 | SCD (0.50) | SCDIRAK4P2RX7MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |