Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310026 | 0.85 | MAPK8 (0.36) | EGLN1CYP2C9MAPK11MAPK14TRPA1 | |
| SCHEMBL5312642 | 0.85 | SCD (0.36) | EGLN1CYP2C9MAPK11MAPK14P2RX7 | |
| SCHEMBL5312895 | 0.83 | SCD (0.36) | EGLN1CYP2C9MAPK11MAPK14TRPA1 | |
| SCHEMBL5313384 | 0.83 | SCD (0.40) | EGLN1CYP2C9MAPK11MAPK14P2RX7 | |
| SCHEMBL5309204 | 0.80 | SCD (0.37) | EGLN1CYP2C9MAPK11MAPK14CXCR3 | |
| SCHEMBL5312893 | 0.78 | SCD (0.41) | MAPK8SCD | |
| SCHEMBL5306699 | 0.77 | SCD (0.41) | EGLN1MAPK14CXCR3SCD | |
| SCHEMBL5306454 | 0.75 | EGLN1 (0.39) | EGLN1GABRA5 | |
| SCHEMBL5309487 | 0.74 | MAPK14 (0.41) | EGLN1MAPK14SCD | |
| SCHEMBL5309303 | 0.74 | SCD (0.44) | EGLN1CYP2C9MAPK11MAPK14P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |