Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936462 | 0.87 | SMN1; SMN2 (0.53) | HPGDHTTCA12CA1CA2 | |
| SCHEMBL5308940 | 0.81 | SCD (0.58) | KMT2ASCD | |
| SCHEMBL5309233 | 0.80 | SCD (0.60) | SCD | |
| SCHEMBL5312910 | 0.78 | HPGD (0.42) | HPGDHTTCA12CA1CA2 | |
| SCHEMBL5315099 | 0.78 | HPGD (0.39) | HPGDHTTCA12CA1CA2 | |
| SCHEMBL5308957 | 0.76 | SCD (0.55) | HPGDSCD | |
| SCHEMBL19174856 | 0.74 | POLB (0.66) | HPGDHTTCA12CA1CA2 | |
| SCHEMBL27544619 | 0.73 | POLB (0.64) | HPGDHTTCA12CA1CA2 | |
| SCHEMBL5306153 | 0.72 | DCTPP1 (0.49) | SCD | |
| SCHEMBL5315102 | 0.71 | HPGD (0.36) | HPGDHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |