Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128708 | 0.94 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3CNR1ACACB | |
| SCHEMBL4128706 | 0.94 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3CNR1ACACB | |
| SCHEMBL5343070 | 0.91 | HTR2C (0.48) | HTR2CHTR2BSLC6A4SLC6A2HTR2A | |
| SCHEMBL5313624 | 0.90 | HTR2C (0.39) | HTR2CHTR2BSLC6A4SLC6A2HTR2A | |
| SCHEMBL4134674 | 0.88 | HTR2C (0.50) | HTR2CHTR2BSLC6A4SLC6A2HTR2A | |
| SCHEMBL4134676 | 0.88 | HTR2C (0.50) | HTR2CHTR2BSLC6A4SLC6A2HTR2A | |
| SCHEMBL4131900 | 0.85 | HTR2C (0.54) | HTR2CSLC6A4SLC6A3ACACBACACA | |
| SCHEMBL4131902 | 0.85 | HTR2C (0.54) | HTR2CSLC6A4SLC6A3ACACBACACA | |
| SCHEMBL4131945 | 0.83 | HTR2C (0.41) | HTR2CSLC6A4SLC6A2ACACBACACA | |
| SCHEMBL4131941 | 0.83 | HTR2C (0.41) | HTR2CSLC6A4SLC6A2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |