Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | APOB | P04114 | 2/20 | 0.36 |
| ▸ | MTTP | P55157 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131945 | 0.94 | HTR2C (0.41) | HTR2CSLC6A2SLC6A4CYP11B1CYP11B2 | |
| SCHEMBL4131941 | 0.94 | HTR2C (0.41) | HTR2CSLC6A2SLC6A4CYP11B1CYP11B2 | |
| SCHEMBL5343070 | 0.90 | HTR2C (0.48) | HTR2CHTR2BSLC6A2SLC6A4HTR2A | |
| SCHEMBL5312992 | 0.90 | HTR2C (0.39) | HTR2CHTR2BSLC6A2SLC6A4HTR2A | |
| SCHEMBL4134676 | 0.87 | HTR2C (0.50) | HTR2CHTR2BSLC6A2SLC6A4HTR2A | |
| SCHEMBL4134674 | 0.87 | HTR2C (0.50) | HTR2CHTR2BSLC6A2SLC6A4HTR2A | |
| SCHEMBL4131902 | 0.84 | HTR2C (0.54) | HTR2CSLC6A4SLC6A3CHRM3MTNR1B | |
| SCHEMBL4131900 | 0.84 | HTR2C (0.54) | HTR2CSLC6A4SLC6A3CHRM3MTNR1B | |
| SCHEMBL4128708 | 0.83 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3GAAMTNR1B | |
| SCHEMBL4128706 | 0.83 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3GAAMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |