Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131900 | 1.00 | HTR2C (0.54) | HTR2CCTSKGRM2SLC6A4SLC6A3 | |
| SCHEMBL5343070 | 0.94 | HTR2C (0.48) | HTR2CCTSKGRM2SLC6A4SLC6A3 | |
| SCHEMBL4128708 | 0.90 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3MTNR1BACACB | |
| SCHEMBL4128706 | 0.90 | CNR1 (0.42) | HTR2CSLC6A4SLC6A3MTNR1BACACB | |
| SCHEMBL4131945 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4MTNR1BACACBACACA | |
| SCHEMBL4131941 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4MTNR1BACACBACACA | |
| SCHEMBL5312992 | 0.85 | HTR2C (0.39) | HTR2CSLC6A4SLC6A3MTNR1BACACB | |
| SCHEMBL5313624 | 0.84 | HTR2C (0.39) | HTR2CSLC6A4SLC6A3MTNR1BACACB | |
| SCHEMBL4126563 | 0.84 | SLC6A3 (0.44) | HTR2CCTSKGRM2SLC6A4SLC6A3 | |
| SCHEMBL4126559 | 0.84 | SLC6A3 (0.44) | HTR2CCTSKGRM2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203750-A1 | 5-HT2C Receptor Agonists as Anorectic Agents | HTR2C, HTR2A, HTR5A | HTR2C 1/4885CTSK 4615/4885GRM2 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.