Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313120 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL15741907 | 0.88 | EPHX2 (0.43) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL15741908 | 0.88 | EPHX2 (0.43) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL4855400 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL2244922 | 0.83 | EPHX2 (0.42) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL9811897 | 0.83 | EPHX2 (0.42) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL2254208 | 0.83 | EPHX2 (0.42) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL2247731 | 0.81 | KMT2A (0.41) | SMN1; SMN2EPHX2LMNAKMT2AALDH1A1 | |
| Glutamine SCHEMBL3974114 | 0.80 | BLM (0.47) | SMN1; SMN2LMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL21167241 | 0.78 | KMT2A (0.41) | SMN1; SMN2EPHX2LMNAKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922862-A1 | COMPLEX-FORMATION-MODULATING AGENTS AND USES THEREFOR | Queensland University Of Technology (AU) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014078896-A1 | COMPLEX-FORMATION-MODULATING AGENTS AND USES THEREFOR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2014-05-30 | — | — | WO | disclosed |
| WO-2007045873-A2 | MEDICAL USES AND THERAPIES BASED UPON THE ACTION OF AZUROCIDIN ON IGFBP-1 | RUTHERFORD, JODIE (GB) | 2007-04-26 | — | — | WO | disclosed |
| EP-1530589-A2 | FRAGMENTS OF PROINSULIN C-PEPTIDE | Creative Peptides Sweden AB (SE) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004016647-A2 | FRAGMENTS OF PROINSULIN C-PEPTIDE | CREATIVE PEPTIDES SWEDEN AB (SE) | 2004-02-26 | — | — | WO | disclosed |