Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244922 | 1.00 | EPHX2 (0.42) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL2254208 | 1.00 | EPHX2 (0.42) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL2247731 | 0.98 | KMT2A (0.41) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL21167241 | 0.95 | KMT2A (0.41) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL4621861 | 0.91 | KMT2A (0.44) | EPHX2KMT2AALOX15BLMPMP22 | |
| SCHEMBL5323996 | 0.91 | KMT2A (0.44) | EPHX2KMT2AALOX15BLMPMP22 | |
| SCHEMBL29501687 | 0.86 | EPHX2 (0.53) | EPHX2SMN1; SMN2LMNAMMP2MMP9 | |
| SCHEMBL5313119 | 0.83 | SMN1; SMN2 (0.36) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL5313120 | 0.83 | SMN1; SMN2 (0.36) | EPHX2KMT2ASMN1; SMN2ALOX15BLM | |
| SCHEMBL9811947 | 0.83 | ALDH1A1 (0.40) | EPHX2SMN1; SMN2LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154343-B1 | ADSORBENT | Research Development Corporation of Japan (JP) | 1991-06-19 | — | — | EP | disclosed |
| US-4785021-A | OPTICAL RESOLUTION | RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) | 1988-11-15 | — | — | US | disclosed |
| US-4747956-A | CROSSLINKED POLYAMINO ACID | RESEARCH DEVELOPMENT CORPORATION (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4694044-A | Adsorbent | RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) | 1987-09-15 | — | — | US | disclosed |
| EP-0154343-A2 | Adsorbent | Research Development Corporation of Japan (JP) | 1985-09-11 | — | — | EP | disclosed |