Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295523 | 0.84 | CA1 (0.56) | KDM4EPOLBTSHRRECQLKMT2A | |
| SCHEMBL8837050 | 0.81 | CA12 (0.70) | KDM4EKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL26965437 | 0.79 | KMT2A (0.68) | KDM4EPOLBTSHRRECQLKMT2A | |
| SCHEMBL12765264 | 0.79 | GAA (0.61) | KDM4EKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9080 | 0.78 | GAA (0.66) | POLBTSHRKMT2AGAAMEN1 | |
| SCHEMBL11252666 | 0.78 | KMT2A (0.66) | KDM4EPOLBTSHRRECQLKMT2A | |
| SCHEMBL423037 | 0.78 | CA2 (0.68) | KDM4EPOLBTSHRRECQLKMT2A | |
| SCHEMBL7529131 | 0.77 | GAA (0.59) | KDM4EKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL25412009 | 0.77 | GAA (0.63) | KDM4ETSHRKMT2AGAAMEN1 | |
| SCHEMBL7749669 | 0.77 | GAA (0.63) | KDM4EPOLBTSHRRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824837-A1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | Pfizer, Inc. (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006051378-A1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2006-05-18 | — | — | WO | disclosed |