SCHEMBL7749669

SCHEMBL7749669

O=C(CNCc1ccccc1)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.63
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
GID4 Q8IVV7 1/20 0.58
MCL1 Q07820 1/20 0.58
HPGD P15428 3/20 0.57
TSHR P16473 1/20 0.57
ALDH1A1 P00352 4/20 0.57
KDM4E B2RXH2 1/20 0.57
HTT P42858 1/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
RECQL P46063 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30074498 0.89 ALDH1A1 (0.54) GAAKMT2AMEN1GID4ALDH1A1
SCHEMBL10382127 0.87 ALDH1A1 (0.53) GAAKMT2AMEN1GID4HPGD
SCHEMBL9334106 0.85 GAA (0.56) GAAKMT2AMEN1MCL1HPGD
SCHEMBL23637058 0.85 GAA (0.56) GAAKMT2AMEN1MCL1HPGD
SCHEMBL13073335 0.85 EPHX1 (0.62) GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL28044793 0.85 PKM (0.63) GAAKMT2AMEN1MCL1HPGD
SCHEMBL3689926 0.84 MEP1B (0.68) GAAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL25412009 0.84 GAA (0.63) GAAKMT2AMEN1MCL1HPGD
SCHEMBL10380701 0.84 ALDH1A1 (0.50) GAAKMT2AMEN1HPGDALDH1A1
SCHEMBL7747993 0.84 ALDH1A1 (0.50) GAAKMT2AMEN1GID4MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698170-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS Eberhard-Karls-Universität Tübingen (DE) 2026-02-25 EP disclosed
WO-2024218333-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) 2024-10-24 WO disclosed
US-20110319636-A1 METHOD FOR PREPARATION OF AMIDES FROM ALCOHOLS AND AMINES BY EXTRUSION OF HYDROGEN TECHNICAL UNIVERSITY OF DENMARK 2011-12-29 US disclosed
EP-1155327-A1 BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY CHIRON CORPORATION (US) 2001-11-21 EP disclosed
WO-2001033230-A2 BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY CHIRON CORPORATION (US) 2001-05-10 WO disclosed
US-6017660-A PIGMENTED INK COMPRISING ADDITION POLYMER MONOMER, PHOTOINITATOR MIXTURE CONTAINING A DIARYLIODONIUM SALT, SENSITIZER FOR 2-METHYL-4,6-BIS(TRICHLOROMETHYL)-S-TRIAZINE, AND ELECTRON DONOR COMPOUND; PHOTOCURABLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-01-25 US disclosed
EP-0216746-B1 PROCESS TO PREPARE 2,5-DIKETOPIPERAZINES Monsanto Company (US) 1990-10-24 EP disclosed
US-4694081-A FUNGICIDES MONSANTO COMPANY (US) 1987-09-15 US disclosed
EP-0216746-A2 Process to prepare 2,5-diketopiperazines Monsanto Company (US) 1987-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319636-A1 METHOD FOR PREPARATION OF AMIDES FROM ALCOHOLS AND AMINES BY EXTRUSION OF HYDROGEN ADH1C, ADH5, ADH1A GAA 3883/4885KMT2A 1117/4885MEN1 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.