Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MPI | P34949 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807575 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL15648890 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL377487 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL31192183 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6702846 | 0.81 | KDM4E (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10050059 | 0.80 | KDM4E (0.77) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL1934130 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29400098 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6050565 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5336901 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |