Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16460086 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL15648890 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5313245 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30293261 | 0.75 | HSD17B10 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14486713 | 0.75 | HSD17B10 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7119124 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL19583371 | 0.69 | HSD17B10 (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL19242935 | 0.69 | KDM4E (0.66) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14907054 | 0.69 | KDM4E (0.79) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7032301 | 0.69 | HSD17B10 (0.61) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |