Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979699 | 0.86 | DAO (0.63) | DAOGSK3BCTNNB1WNT3ACES1 | |
| SCHEMBL6917802 | 0.80 | DAO (0.60) | DAOGSK3BMEN1KMT2ANPC1 | |
| SCHEMBL3867877 | 0.80 | DAO (0.55) | DAOGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL15979698 | 0.78 | GSK3B (0.62) | DAOGSK3BCTNNB1WNT3ACES1 | |
| SCHEMBL28474265 | 0.78 | DAO (0.57) | DAOGSK3BMEN1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL30785229 | 0.77 | DAO (0.45) | DAOFAAHCES1MEN1KMT2A | |
| SCHEMBL15979708 | 0.77 | DAO (0.52) | DAOGSK3BCTNNB1WNT3AMEN1 | |
| SCHEMBL2773258 | 0.76 | DAO (0.55) | DAOGSK3B | |
| SCHEMBL7253264 | 0.75 | DAO (0.59) | DAOHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL15979705 | 0.74 | RAB9A (0.68) | GSK3BCTNNB1WNT3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-RE39420-E1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-12-05 | — | — | US | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |