SCHEMBL5313356

SCHEMBL5313356

COCN(C(=O)Nc1ccc(SC)cc1F)C(=O)c1c(F)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.38
GAA P10253 3/20 0.38
LMNA P02545 3/20 0.38
PKM P14618 1/20 0.38
POLB P06746 1/20 0.38
ALDH1A1 P00352 4/20 0.37
RAB9A P51151 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
MEN1 O00255 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PTGES O14684 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315021 0.93 HTT (0.37) KMT2APOLBALDH1A1RAB9AL3MBTL1
SCHEMBL5313867 0.90 MAPT (0.38) KMT2AGAALMNAPKMPOLB
SCHEMBL5314390 0.90 LMNA (0.36) KMT2AGAALMNAPKMPOLB
SCHEMBL5316854 0.86 TLR7 (0.37) KMT2AGAALMNAPKMPOLB
SCHEMBL5314189 0.86 TLR7 (0.37) KMT2AGAALMNAPKMPOLB
SCHEMBL5316114 0.85 KMT2A (0.35) KMT2AGAALMNAPKMALDH1A1
SCHEMBL5314392 0.84 LMNA (0.38) KMT2AGAALMNAPKMPOLB
SCHEMBL5315683 0.82 KMT2A (0.47) KMT2ALMNAPKMPOLBALDH1A1
SCHEMBL5318469 0.82 SMN1; SMN2 (0.36) KMT2AGAALMNAPOLBALDH1A1
SCHEMBL5335591 0.80 HTT (0.34) KMT2APOLBALDH1A1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066496-A1 BENZOYLUREA COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 WO disclosed