SCHEMBL5313488

SCHEMBL5313488

CN(C(=O)c1c(F)cccc1F)C(=O)N(CCOC1CCCCO1)c1ccc(SC(F)(F)F)cc1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314883 0.85 MEN1 (0.33) MEN1KMT2AL3MBTL1KDM4C
SCHEMBL5312744 0.81 ABL1 (0.34) TDP1
SCHEMBL4145428 0.79 RORC (0.36) MEN1KMT2ATDP1
SCHEMBL5313933 0.78 TDP1 (0.31) TDP1
SCHEMBL5310976 0.78 MAPT (0.34) MEN1KMT2ATDP1L3MBTL1ALDH1A1
SCHEMBL5311759 0.77 RORC (0.32) TDP1
SCHEMBL5314885 0.77 KDM4E (0.32) TDP1
SCHEMBL5311842 0.76 ALDH1A1 (0.43) MEN1KMT2ATDP1L3MBTL1ALDH1A1
SCHEMBL5311816 0.76
SCHEMBL14494345 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066496-A1 BENZOYLUREA COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 WO disclosed