Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4254122 | 0.99 | MEN1 (0.35) | DRD3HTR2ALMNAKCNH2MEN1 | |
| SCHEMBL4251388 | 0.85 | KCNH2 (0.36) | DRD3HTR2ALMNAKCNH2MEN1 | |
| Hydrochloric Acid SCHEMBL4249950 | 0.84 | KCNH2 (0.36) | DRD3HTR2ALMNAKCNH2MEN1 | |
| SCHEMBL4987894 | 0.83 | HTR1B (0.43) | DRD3HTR2ALMNAKCNH2KMT2A | |
| Hydrochloric Acid SCHEMBL6992659 | 0.82 | HTR1B (0.43) | DRD3HTR2ALMNAKCNH2KMT2A | |
| SCHEMBL4794533 | 0.73 | NFKB1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL429657 | 0.70 | NFKB1 (0.39) | SMN1; SMN2LTB4RLTB4R2NFKB1NFKB2 | |
| SCHEMBL5311384 | 0.69 | HTR1B (0.46) | DRD3LMNAKCNH2MEN1TP53 | |
| SCHEMBL14457146 | 0.68 | LTB4R (0.45) | LTB4RLTB4R2NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL4246638 | 0.68 | HTR1B (0.46) | DRD3LMNAKCNH2MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053093-A1 | CHROMAN COMPOUNDS AS 5 HT1B ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-05-10 | — | — | WO | disclosed |