Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306913 | 0.80 | CDK2 (0.40) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL5311858 | 0.80 | LMNA (0.43) | KDM4ELMNAMAPTHPGDMAPK1 | |
| SCHEMBL5303639 | 0.79 | LMNA (0.44) | ALDH1A1KDM4ELMNAF2MAPT | |
| SCHEMBL5310087 | 0.78 | CYP1A2 (0.44) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL5303482 | 0.77 | MAPT (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5304358 | 0.77 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5306328 | 0.77 | F2 (0.47) | ALDH1A1KDM4EF2MAPTMEN1 | |
| SCHEMBL5332325 | 0.76 | MAPT (0.45) | LMNAMAPTSMN1; SMN2CLK4GAA | |
| SCHEMBL5307225 | 0.76 | MAPT (0.48) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL5303090 | 0.75 | MAPT (0.51) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |