Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332325 | 0.89 | MAPT (0.45) | MAPTCLK4KCNN3POLBLMNA | |
| SCHEMBL5303639 | 0.87 | LMNA (0.44) | MAPTHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5306369 | 0.87 | TP53 (0.48) | CYP1A2CYP3A4CYP2C19MAPTHPGD | |
| SCHEMBL5306913 | 0.83 | CDK2 (0.40) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL5306328 | 0.82 | F2 (0.47) | CYP1A2CYP2C19MAPTHPGDALDH1A1 | |
| SCHEMBL5304358 | 0.82 | MAPT (0.45) | CYP1A2MAPTTDP1MEN1KMT2A | |
| SCHEMBL5311858 | 0.81 | LMNA (0.43) | MAPTHPGDKDM4EMAPK1KCNN3 | |
| SCHEMBL5306559 | 0.81 | KDM4E (0.47) | MAPTHPGDTSHRALDH1A1KDM4E | |
| SCHEMBL5303090 | 0.81 | MAPT (0.51) | MAPTHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5310789 | 0.79 | TSHR (0.50) | MAPTHPGDTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |