Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543454 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL8866011 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL398923 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL720162 | 0.81 | EGLN2 (0.51) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL5700012 | 0.79 | KDM4E (0.35) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL518833 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL27877482 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL9956653 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL20406114 | 0.79 | PLK1 (0.45) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 | |
| SCHEMBL28177117 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613330-A | 3-Bromopyridine derivative, continuous synthesis method and application thereof | 苏州汉德创宏生化科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-110423234-A | Thiosemicarbazone derivative of the segment containing indoles and its preparation method and application | UNIV ZHENGZHOU | 2019-11-08 | — | — | CN | claimed |
| WO-2026106912-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-05-21 | — | — | WO | disclosed |
| US-12630566-B2 | KRas G12D inhibitors | Mirati Therapeutics, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-12624053-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260070930-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2026-03-12 | — | — | US | disclosed |
| EP-4696316-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695228-A1 | SYNTHESIS OF RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695233-A2 | SYNTHESIS OF RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260042740-A1 | RAS INHIBITORS | REVOLUTION MEDICINES INC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4054719-B1 | RAS INHIBITORS | REVOLUTION MEDICINES INC (US) | 2026-02-11 | — | — | EP | disclosed |
| US-8546442-B2 | Pyrazolopiperidine compounds as CCR1 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| US-20120322790-A1 | Pyrazolopiperidine Compounds As CCR1 Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120322790-A1 | Pyrazolopiperidine Compounds As CCR1 Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2012087782-A1 | PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| WO-2007065939-A1 | SUBSTITUTED THIAZOLE DERIVATIVES AND THEIR USES AS TYROSINE KINASE INHIBITORS | AB SCIENCE (FR) | 2007-06-14 | — | — | WO | disclosed |
| CN-1297540-C | Pyridylethanol (phenylethyl) amine derivatives as cholesterol biosynthesis inhibitors, process for their preparation and pharmaceutical compositions containing them | LEK FARMACEVTSKA DRUZBA DD (SI) | 2007-01-31 | — | — | CN | disclosed |
| CN-1284064-A | 2,3-substituted indole compounds as cox-2 inhibitors | PFIZER PHARMA (US) | 2001-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | DDT, OXER1, OSTC | ALDH1A1 1259/4885KDM4E 940/4885L3MBTL1 808/4885 |
| US-20260070930-A1 | RAS INHIBITORS | KRAS, NRAS, RIN1 | ALDH1A1 2609/4885KDM4E 3358/4885L3MBTL1 1851/4885 |
| US-20260042740-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 4551/4885KDM4E 1571/4885L3MBTL1 2146/4885 |
| US-12624053-B2 | Ras inhibitors | KRAS, NRAS, HMGCR | ALDH1A1 3405/4885KDM4E 2746/4885L3MBTL1 2718/4885 |
| US-12630566-B2 | KRas G12D inhibitors | KRAS, NRAS, HRAS | ALDH1A1 1816/4885KDM4E 2825/4885L3MBTL1 3074/4885 |
| US-20120322790-A1 | Pyrazolopiperidine Compounds As CCR1 Receptor Antagonists | CCR1, CCR3, CCR4 | ALDH1A1 719/4885KDM4E 4173/4885L3MBTL1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.