Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | AGER | Q15109 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27877482 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL8866011 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL9956653 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL518833 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL29543454 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL5313640 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL78249 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL31356480 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL15312235 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| Silver SCHEMBL28907852 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247372-A | Preparation method of oxindole compound | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2023-12-19 | — | — | CN | claimed |
| CN-116655526-B | Method for synthesizing 3-bromo-2- (bromomethyl) pyridine | 济南泺合医药技术有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116655526-A | Method for synthesizing 3-bromo-2- (bromomethyl) pyridine | 济南泺合医药技术有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-110204484-B | The method comprises the following steps of 18 F-labeled fluoropyridine formylglycine, and preparation method and application thereof | 山西医科大学第一医院 | 2023-07-21 | — | — | CN | claimed |
| CN-103201276-B | Indole derivatives | RICHTER GEDEON NYRT | 2015-02-25 | — | — | CN | claimed |
| CN-103201276-A | Indole derivatives | RICHTER GEDEON NYRT | 2013-07-10 | — | — | CN | claimed |
| EP-2456763-A1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Novartis AG (CH) | 2012-05-30 | — | — | EP | claimed |
| EP-2121635-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | claimed |
| WO-2008078196-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2008-07-03 | — | — | WO | claimed |
| EP-1781339-A1 | COMPOUNDS OF THE INVENTIONS OF GUANYLYL CYCLASE C | THOMAS JEFFERSON UNIVERSITY (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006012264-A1 | COMPOUNDS OF THE INVENTIONS OF GUANYLYL CYCLASE C | THOMAS JEFFERSON UNIVERSITY (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050287067-A1 | Compounds of the inventions of guanylyl cyclase C | THOMAS JEFFERSON UNIVERSITY | 2005-12-29 | — | — | US | claimed |
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-05-14 | — | — | US | disclosed |
| EP-4635949-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| US-4104274-A | 1-Substituted-2-(2-pyridinyl)ethanone N-oxides | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4076720-A | 1-Substituted-2-(2-pyridinyl)ethanone N-oxides | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4056619-A | 1-Substituted-2-(2-pyridinyl)ethanone N-oxides | WARNER-LAMBERT COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
| US-3963733-A | 3-(P-methoxybenzylthio)2-non-oxocarbonylic pyridines | SMITHKLINE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050287067-A1 | Compounds of the inventions of guanylyl cyclase C | GUCY1B2, GUCY1A1, GUCY1A2 | KDM4E 2886/4885ALDH1A1 1143/4885MAPT 4512/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | KDM4E 454/4885ALDH1A1 3132/4885MAPT 785/4885 |
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | TRHR, NR3C2, THRB | KDM4E 4548/4885ALDH1A1 1063/4885MAPT 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.