Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530611 | 1.00 | MAOB (0.53) | MAOBNR4A2LTB4RLTB4R2SMPD1 | |
| SCHEMBL5310252 | 0.92 | FFAR1 (0.47) | MAOBNR4A2SRD5A2PLA2G4BKMT2A | |
| SCHEMBL5310255 | 0.92 | FFAR1 (0.47) | MAOBNR4A2SRD5A2PLA2G4BKMT2A | |
| SCHEMBL5314652 | 0.87 | PLA2G4B (0.47) | LTB4RLTB4R2PLA2G4BMEN1KMT2A | |
| SCHEMBL5314655 | 0.87 | PLA2G4B (0.47) | LTB4RLTB4R2PLA2G4BMEN1KMT2A | |
| SCHEMBL5310840 | 0.85 | PPARG (0.43) | MAOBPLA2G4BMEN1KMT2AFFAR1 | |
| SCHEMBL5310838 | 0.85 | PPARG (0.43) | MAOBPLA2G4BMEN1KMT2AFFAR1 | |
| SCHEMBL5309894 | 0.83 | PLA2G4B (0.50) | MAOBSRD5A2PLA2G4BKMT2AFFAR1 | |
| SCHEMBL5309885 | 0.83 | PLA2G4B (0.50) | MAOBSRD5A2PLA2G4BKMT2AFFAR1 | |
| SCHEMBL5335188 | 0.83 | FFAR1 (0.43) | LTB4RLTB4R2SRD5A2PLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |