Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314655 | 1.00 | PLA2G4B (0.47) | PLA2G4BPTPN7PPARDPPARGPPARA | |
| SCHEMBL5331241 | 0.92 | PLA2G4B (0.50) | PLA2G4BPTPN7PPARDPPARGPPARA | |
| SCHEMBL5331237 | 0.92 | PLA2G4B (0.50) | PLA2G4BPTPN7PPARDPPARGPPARA | |
| SCHEMBL5310046 | 0.89 | PLA2G4B (0.46) | PLA2G4BPTPN7PPARDPPARGPPARA | |
| SCHEMBL5310042 | 0.89 | PLA2G4B (0.46) | PLA2G4BPTPN7PPARDPPARGPPARA | |
| SCHEMBL5310255 | 0.87 | FFAR1 (0.47) | PLA2G4BPPARDPPARGPPARAKMT2A | |
| SCHEMBL5313645 | 0.87 | MAOB (0.53) | PLA2G4BMEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL5310252 | 0.87 | FFAR1 (0.47) | PLA2G4BPPARDPPARGPPARAKMT2A | |
| SCHEMBL14530611 | 0.87 | MAOB (0.53) | PLA2G4BMEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL5426947 | 0.84 | PPARG (0.46) | PLA2G4BPPARDPPARGPPARANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |