Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310252 | 1.00 | FFAR1 (0.47) | FFAR1PLA2G4BSRD5A2AKR1C3SMN1; SMN2 | |
| SCHEMBL5309885 | 0.92 | PLA2G4B (0.50) | FFAR1PLA2G4BSRD5A2AKR1C3SMN1; SMN2 | |
| SCHEMBL5335192 | 0.92 | FFAR1 (0.43) | FFAR1PLA2G4BSRD5A2AKR1C3ALDH1A1 | |
| SCHEMBL5335188 | 0.92 | FFAR1 (0.43) | FFAR1PLA2G4BSRD5A2AKR1C3ALDH1A1 | |
| SCHEMBL5309894 | 0.92 | PLA2G4B (0.50) | FFAR1PLA2G4BSRD5A2AKR1C3SMN1; SMN2 | |
| SCHEMBL14530611 | 0.92 | MAOB (0.53) | FFAR1PLA2G4BSRD5A2MAOBNR4A2 | |
| SCHEMBL5313553 | 0.92 | SRD5A2 (0.49) | FFAR1PLA2G4BSRD5A2AKR1C3SMN1; SMN2 | |
| SCHEMBL5313558 | 0.92 | SRD5A2 (0.49) | FFAR1PLA2G4BSRD5A2AKR1C3SMN1; SMN2 | |
| SCHEMBL5313645 | 0.92 | MAOB (0.53) | FFAR1PLA2G4BSRD5A2MAOBNR4A2 | |
| SCHEMBL5315649 | 0.90 | LMNA (0.44) | FFAR1SRD5A2AKR1C3PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |