Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.51 |
| ▸ | WNT3A | P56704 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167035 | 0.86 | NPC1 (0.55) | NPC1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL315926 | 0.84 | CTNNB1 (0.54) | NPC1LMNACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL3949461 | 0.84 | CTNNB1 (0.60) | CTNNB1WNT3ASMN1; SMN2TDP1MAPT | |
| SCHEMBL20945667 | 0.84 | LMNA (0.43) | NPC1LMNASMN1; SMN2TDP1CES2 | |
| SCHEMBL15058686 | 0.83 | RXFP1 (0.51) | NPC1LMNACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL30666322 | 0.83 | CTNNB1 (0.50) | CTNNB1WNT3ASMN1; SMN2TDP1MAPT | |
| SCHEMBL30666326 | 0.83 | RXFP1 (0.51) | NPC1LMNACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL8384471 | 0.81 | CTNNB1 (0.54) | CTNNB1WNT3APOLBCES2MAPT | |
| SCHEMBL4686898 | 0.81 | LMNA (0.61) | NPC1LMNATDP1POLBMAPT | |
| SCHEMBL15058334 | 0.81 | ERCC5 (0.51) | LMNASMN1; SMN2MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062797-A1 | AMINO-SUBSTITUTED AZO-HETEROCYCLIC COMPOUNDS FOR TREATING INFLAMMATORY CONDITIONS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007062677-A1 | THIAZOLYL- AND PYRIMIDINYL-ACETIC ACIDS AND THEIR USE AS CRTH2 RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |