Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832685 | 0.95 | LMNA (0.57) | LMNAHTR7L3MBTL1NPC1RAB9A | |
| SCHEMBL2743554 | 0.90 | NPC1 (0.68) | LMNAHTR7L3MBTL1NPC1RAB9A | |
| SCHEMBL1360326 | 0.90 | HTR7 (0.65) | LMNAHTR7L3MBTL1NPC1RAB9A | |
| SCHEMBL10749473 | 0.86 | KMT2A (0.61) | LMNAL3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL314260 | 0.84 | KMT2A (0.54) | LMNAHTR7NPC1RAB9AMAPT | |
| SCHEMBL1374042 | 0.84 | HSD17B3 (0.61) | L3MBTL1NPC1RAB9AMAPTGAA | |
| SCHEMBL29217284 | 0.83 | HTR7 (0.56) | LMNAHTR7L3MBTL1NPC1RAB9A | |
| Propane SCHEMBL27304878 | 0.83 | KMT2A (0.53) | LMNAHTR7NPC1RAB9AMAPT | |
| SCHEMBL20945667 | 0.83 | LMNA (0.43) | LMNAL3MBTL1NPC1MAPTGAA | |
| SCHEMBL6650021 | 0.83 | LMNA (0.61) | LMNAL3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004639-A2 | PROCESSES FOR THE SYNTHESIS OF AZETIDINONE | Teva Pharmaceutical Industries Ltd (IL) | 2008-12-24 | — | — | EP | disclosed |
| US-20080032964-A1 | Process for the synthesis of azetidinone | TEVA PHARMACEUTICALS USA, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2007120824-A2 | PROCESSES FOR THE SYNTHESIS OF AZETIDINONE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032964-A1 | Process for the synthesis of azetidinone | CYP46A1, APOB, CYP51A1 | LMNA 1910/4885HTR7 1119/4885L3MBTL1 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.