Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312870 | 0.91 | MAOB (0.49) | MAOBHPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10622985 | 0.81 | MAOB (0.50) | MAOBRAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29673576 | 0.81 | MAPT (0.50) | LMNARAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL22187300 | 0.81 | MAPT (0.50) | LMNARAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28171416 | 0.78 | ALPL (0.44) | MAOBLMNAKMT2AALDH1A1 | |
| SCHEMBL11723690 | 0.78 | TSHR (0.54) | MAOBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL1436145 | 0.77 | THRB (0.65) | MAOBLMNAHPGDRAB9AKMT2A | |
| SCHEMBL22187554 | 0.77 | MAPT (0.49) | LMNARAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29673690 | 0.77 | MAPT (0.49) | LMNARAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9000081 | 0.77 | STS (0.53) | MAOBRAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |