Sugi Predict

Sugi Predict / Compounds / SCHEMBL531432

SCHEMBL531432

SCHEMBL531432

Cc1ccc(S(=O)(=O)O)c(C(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.47
▸ TRPA1 O75762 1/20 0.47
▸ CHRM1 P11229 1/20 0.47
▸ SLC6A2 P23975 1/20 0.47
▸ ADRA1A P35348 1/20 0.47
▸ HTR2B P41595 1/20 0.47
▸ FABP3 P05413 1/20 0.44
▸ FABP4 P15090 1/20 0.44
▸ FABP5 Q01469 1/20 0.44
▸ ACHE P22303 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ GAA P10253 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ CASP6 P55212 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ELAVL1 Q15717 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101570 0.89 LMNA (0.38) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL30716899 0.89 LMNA (0.38) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL30666645 0.89 LMNA (0.38) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL30667146 0.89 LMNA (0.38) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL8464278 0.87 LMNA (0.37) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL906246 0.85 LMNA (0.36) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL242353 0.85 LMNA (0.36) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL21403141 0.85 LMNA (0.36) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL28435125 0.85 LMNA (0.36) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL1979988 0.85 LMNA (0.52) LMNATRPA1CHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023108048-A2 METHODS OF PREPARING SUBSTITUTED PYRAZOLOPYRIMIDINES KSQ Therapeutics, Inc. (US) 2023-06-15 — — WO claimed
EP-1756126-B1 PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS ICL IP AMERICA INC (US) 2012-02-08 — — EP claimed
JP-4175376-A — — None — — JP disclosed
CN-118369094-A Process for preparing substituted pyrazolopyrimidines KSQ治疗公司 2024-07-19 — — CN disclosed
CN-114113346-B Detection method of ethyl p-toluenesulfonate and isopropyl p-toluenesulfonate in dabigatran etexilate bulk drug or preparation 石药集团恩必普药业有限公司 2024-01-12 — — CN disclosed
WO-2023108048-A2 METHODS OF PREPARING SUBSTITUTED PYRAZOLOPYRIMIDINES KSQ Therapeutics, Inc. (US) 2023-06-15 — — WO disclosed
CN-109134229-B Method for preparing cypress oleyl alcohol 中国农业科学院农业环境与可持续发展研究所 2020-09-04 — — CN disclosed
US-10626287-B2 Resin composition for underlayer film formation, layered product, method for forming pattern, and process for producing device FUJIFILM CORPORATION (JP) 2020-04-21 — — US disclosed
US-10344177-B2 Under layer film-forming composition for imprints and method for forming pattern FUJIFILM CORPORATION (JP) 2019-07-09 — — US disclosed
US-10246605-B2 Resin composition for underlayer film formation, layered product, method for forming pattern, imprint forming kit, and process for producing device FUJIFILM CORPORATION (JP) 2019-04-02 — — US disclosed
US-10191375-B2 Resin composition for underlayer film formation, layered product, method for forming pattern, imprint forming kit and process for producing device FUJIFILM CORPORATION (JP) 2019-01-29 — — US disclosed
WO-2016103166-A1 CO-CRYSTALS OF 5-AMINO-2-OXOTHIAZOLO[4,5-D]PYRIMIDIN-3(2H)-YL-5-HYDROXYMETHYL TETRAHYDROFURAN-3-YL ACETATE AND METHODS FOR PREPARING AND USING THE SAME F. HOFFMANN-LA ROCHE AG (CH) 2016-06-30 — — WO disclosed
US-20160176899-A1 CO-CRYSTALS OF 5-AMINO-2-OXOTHIAZOLO[4,5-D]PYRIMIDIN-3(2H)-YL-5-HYDROXYMETHYL TETRAHYDROFURAN-3-YL ACETATE AND METHODS FOR PREPARING AND USING THE SAME HOFFMANN-LA ROCHE INC. 2016-06-23 — — US disclosed
EP-2980831-A1 UNDERLAYER-FILM-FORMING COMPOSITION FOR IMPRINTING, AND PATTERN FORMATION METHOD Fujifilm Corporation (JP) 2016-02-03 — — EP disclosed
US-20160009946-A1 UNDER LAYER FILM-FORMING COMPOSITION FOR IMPRINTS AND METHOD FOR FORMING PATTERN FUJIFILM CORPORATION (JP) 2016-01-14 — — US disclosed
JP-H04175376-A THERMOSETTING COMPOSITION NIPPON OIL & FATS CO LTD 1992-06-23 — — JP disclosed
EP-0229944-A2 Novel tetrahydroisoquinoline derivatives SYNTEX (U.S.A.) INC. (US) 1987-07-29 — — EP disclosed
US-4681889-A ANGINA, HYPERTENSION, CONGESTIVE HEART FAILURE SYNTEX (U.S.A.) INC. (US) 1987-07-21 — — US disclosed
US-4613606-A CARDIOVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1986-09-23 — — US disclosed
US-4065613-A ETHYLENEBRANCHING AGENTSATACTIC, AMORPHOUS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160176899-A1 CO-CRYSTALS OF 5-AMINO-2-OXOTHIAZOLO[4,5-D]PYRIMIDIN-3(2H)-YL-5-HYDROXYMETHYL TETRAHYDROFURAN-3-YL ACETATE AND METHODS FOR PREPARING AND USING THE SAME SLC10A1, HCCS, HAVCR2 LMNA 3981/4885TRPA1 4773/4885CHRM1 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.