Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776505 | 0.87 | GAA (0.36) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30667146 | 0.85 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL9101570 | 0.85 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30716899 | 0.85 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL531432 | 0.85 | LMNA (0.47) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30666645 | 0.85 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL625780 | 0.84 | GAA (0.35) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL8464278 | 0.84 | LMNA (0.37) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL906246 | 0.82 | LMNA (0.36) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21403141 | 0.82 | LMNA (0.36) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242314-B2 | Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride | WASHINGTON UNIVERSITY (US) | 2022-02-08 | — | — | US | claimed |
| US-20170197912-A1 | SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE | WASHINGTON UNIVERSITY (US) | 2017-07-13 | — | — | US | claimed |
| WO-2008132211-A1 | AMINO-QUINAZOLINONE DERIVATIVES FOR USE AS RADIOTRACERS AND IMAGING AGENTS | NOVARTIS AG (CH) | 2008-11-06 | — | — | WO | claimed |
| WO-2025085387-A1 | SUBSTITUTED-ALKENYL-INDAZOLES FOR IMAGING AGGREGATED TAU IN TAUOPATHIES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |
| US-20240409499-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-12-12 | — | — | US | disclosed |
| US-12006302-B2 | Tau PET imaging ligands | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-11 | — | — | US | disclosed |
| CN-117624166-A | Triazole derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| US-11673855-B2 | Voltage gated sodium channel imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220267254-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION | 2022-08-25 | — | — | US | disclosed |
| WO-2009079683-A1 | TRANSLOCATOR PROTEIN LIGANDS | THE UNIVERSITY OF SYDNEY (AU) | 2009-07-02 | — | — | WO | disclosed |
| WO-2008151003-A2 | NOVEL FLUORINE-18 LABELED RHODAMINE DERIVATIVES FOR MYOCARDIAL PERFUSION IMAGING WITH POSITRON EMISSION TOMOGRAPHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |
| EP-1991526-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | Hammersmith Imanet, Ltd (GB) | 2008-11-19 | — | — | EP | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007057705-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| EP-1718635-A1 | PIPERIDINYL TARGETING COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082889-A1 | PIPERIDINYL TARGETING COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-09-09 | — | — | WO | disclosed |
| US-20040224986-A1 | Piperidinyl targeting compounds that selectively bind integrins | JANSSEN PHARMACEUTICA, NV (BE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197912-A1 | SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE | STX18, GPR119, SLC5A1 | LMNA 4793/4885TRPA1 3707/4885CHRM1 2415/4885 |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | LMNA 2017/4885TRPA1 4691/4885CHRM1 855/4885 |
| US-11242314-B2 | Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride | STX18, GPR119, SLC5A1 | LMNA 4793/4885TRPA1 3707/4885CHRM1 2415/4885 |
| US-20240409499-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | CACNA1B, CACNA1G, CACNA1I | LMNA 959/4885TRPA1 106/4885CHRM1 903/4885 |
| US-20220267254-A1 | VOLTAGE GATED SODIUM CHANNEL IMAGING AGENTS | CACNA1B, CACNA1G, CACNA1I | LMNA 959/4885TRPA1 106/4885CHRM1 903/4885 |
| US-11673855-B2 | Voltage gated sodium channel imaging agents | CACNA1B, CACNA1G, CACNA1I | LMNA 959/4885TRPA1 106/4885CHRM1 903/4885 |
| US-12006302-B2 | Tau PET imaging ligands | MAPT, PSEN1, APP | LMNA 1267/4885TRPA1 3303/4885CHRM1 626/4885 |
| US-20040224986-A1 | Piperidinyl targeting compounds that selectively bind integrins | ITGA5, ITGB5, ITGB1 | LMNA 1296/4885TRPA1 1075/4885CHRM1 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.