Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585954 | 0.85 | CES2 (0.57) | CES2CES1MAPTALDH1A1 | |
| SCHEMBL5824353 | 0.84 | CES2 (0.55) | CES2CES1GPR6L3MBTL1RAB9A | |
| SCHEMBL10747308 | 0.82 | CES2 (0.40) | CES2CES1RAB9ANPC1MAPT | |
| SCHEMBL15539727 | 0.82 | MAP2K1 (0.39) | CES2CES1 | |
| SCHEMBL2916902 | 0.82 | HPGD (0.46) | CES2CES1RAB9ANPC1POLB | |
| SCHEMBL16590409 | 0.82 | CPS1 (0.39) | CES2CES1RAB9ANPC1MAPT | |
| SCHEMBL8348114 | 0.82 | TRPA1 (0.42) | CES2CES1RAB9ANPC1ALDH1A1 | |
| SCHEMBL15541210 | 0.80 | GAA (0.48) | CES2L3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL10803361 | 0.79 | CES2 (0.40) | CES2CES1TDP1ALDH1A1 | |
| SCHEMBL11010263 | 0.79 | CES2 (0.40) | CES2CES1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-1999033790-A1 | INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-08 | — | — | WO | disclosed |