Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309115 | 0.89 | SCD (0.53) | EGLN1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5309728 | 0.85 | ALDH1A1 (0.41) | EGLN1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5312604 | 0.85 | SCD (0.41) | EGLN1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5309059 | 0.84 | SCD (0.53) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5314462 | 0.83 | EGLN1 (0.44) | EGLN1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5307182 | 0.83 | SCD (0.54) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5312488 | 0.82 | SCD (0.47) | EGLN1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5315075 | 0.81 | SCD (0.50) | EGLN1ALDH1A1SMN1; SMN2HPGDSCD | |
| SCHEMBL5307475 | 0.79 | CA2 (0.41) | EGLN1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5306119 | 0.79 | EGLN1 (0.42) | EGLN1ALDH1A1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |