Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.44 |
| ▸ | BECN1 | Q14457 | 4/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 4/20 | 0.38 |
| ▸ | FPR3 | P25089 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126115 | 0.94 | CYP17A1 (0.46) | CYP17A1ACACBACACAKDM1ALATS1 | |
| SCHEMBL4126113 | 0.94 | CYP17A1 (0.46) | CYP17A1ACACBACACAKDM1ALATS1 | |
| SCHEMBL4133947 | 0.90 | HTR2C (0.48) | HTR2CHTR2BKDM1AFPR3FPR2 | |
| SCHEMBL4133943 | 0.90 | HTR2C (0.48) | HTR2CHTR2BKDM1AFPR3FPR2 | |
| SCHEMBL5315451 | 0.88 | HTR2C (0.40) | HTR2CHTR2BKDM1AFPR3FPR2 | |
| SCHEMBL5316467 | 0.88 | CNR1 (0.45) | HTR2CHTR2BKDM1AFPR3FPR2 | |
| SCHEMBL4126477 | 0.82 | HTR2C (0.48) | HTR2CKDM1A | |
| SCHEMBL4126474 | 0.82 | HTR2C (0.48) | HTR2CKDM1A | |
| SCHEMBL4133949 | 0.82 | CNR1 (0.49) | ACACBACACAHTR2CHTR2BKDM1A | |
| SCHEMBL4126559 | 0.82 | SLC6A3 (0.44) | HTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |