Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 4/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126563 | 0.94 | SLC6A3 (0.44) | HTR2CHTR2BSLC6A2HTR2ASLC6A4 | |
| SCHEMBL4126559 | 0.94 | SLC6A3 (0.44) | HTR2CHTR2BSLC6A2HTR2ASLC6A4 | |
| SCHEMBL4133943 | 0.91 | HTR2C (0.48) | HTR2CHTR2BSLC6A4SLC6A3KDM1A | |
| SCHEMBL4133947 | 0.91 | HTR2C (0.48) | HTR2CHTR2BSLC6A4SLC6A3KDM1A | |
| SCHEMBL5316467 | 0.89 | CNR1 (0.45) | HTR2CHTR2BHTR2AKDM1AFPR3 | |
| SCHEMBL5314514 | 0.88 | BCL2 (0.44) | HTR2CHTR2BKDM1AFPR3FPR2 | |
| SCHEMBL5315320 | 0.85 | HTR2C (0.50) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL4127041 | 0.84 | HTR2C (0.56) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL4127039 | 0.84 | HTR2C (0.56) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL4126477 | 0.83 | HTR2C (0.48) | HTR2CKDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |