SCHEMBL5314542

SCHEMBL5314542

Cc1ccc(N(C)c2ccc3nc(Nc4cc(CCN5CCN(C(O)C=O)CC5)ccn4)sc3n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LCK P06239 4/20 0.35
KDR P35968 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314466 0.89 LCK (0.35) LCKKDR
SCHEMBL5333098 0.87 KDR (0.44) LCKKDR
SCHEMBL5314053 0.86 KDR (0.40) LCKKDR
SCHEMBL5335564 0.86 TBK1 (0.41) LCKKDR
SCHEMBL5314538 0.85 KDR (0.44) LCKKDR
SCHEMBL5313056 0.85 LCK (0.34) LCKKDR
SCHEMBL5316940 0.84 KDR (0.42) LCKKDR
SCHEMBL5312891 0.83 KDR (0.44) LCKKDR
SCHEMBL5314698 0.83 KDR (0.43) LCKKDR
SCHEMBL5311889 0.82 TBK1 (0.44) LCKKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007058482-A1 NOVEL INHIBITORS OF PROTEIN KINASE LG LIFE SCIENCES, LTD. (KR) 2007-05-24 WO disclosed