Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314698 | 0.95 | KDR (0.43) | KDRTBK1LCKCHEK1NTRK1 | |
| SCHEMBL5314538 | 0.93 | KDR (0.44) | KDRTBK1LCKCCNT1FLT3 | |
| SCHEMBL5310327 | 0.92 | KDR (0.53) | KDRTBK1LCKCCNT1FLT3 | |
| SCHEMBL5335564 | 0.91 | TBK1 (0.41) | KDRTBK1LCKCCNT1FLT3 | |
| SCHEMBL5312891 | 0.90 | KDR (0.44) | KDRTBK1LCKCCNT1FLT3 | |
| SCHEMBL5309897 | 0.89 | KDR (0.41) | KDRTBK1LCKCHEK1CCNT1 | |
| SCHEMBL5314466 | 0.89 | LCK (0.35) | KDRTBK1LCK | |
| SCHEMBL5314542 | 0.87 | LCK (0.35) | KDRLCK | |
| SCHEMBL5311426 | 0.85 | KDR (0.52) | KDRTBK1LCKCCNT1FLT3 | |
| SCHEMBL5329362 | 0.85 | KDR (0.40) | KDRTBK1LCKCCNT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |