Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314541 | 1.00 | LMNA (0.41) | LMNAPLA2G4BMAPK1L3MBTL1FFAR1 | |
| SCHEMBL5315206 | 0.94 | FFAR1 (0.41) | LMNAPLA2G4BMAPK1L3MBTL1FFAR1 | |
| SCHEMBL5315205 | 0.94 | FFAR1 (0.41) | LMNAPLA2G4BMAPK1L3MBTL1FFAR1 | |
| SCHEMBL5315056 | 0.92 | PLA2G4B (0.49) | LMNAPLA2G4BFFAR1PKMHTT | |
| SCHEMBL5315053 | 0.92 | PLA2G4B (0.49) | LMNAPLA2G4BFFAR1PKMHTT | |
| SCHEMBL14530608 | 0.91 | PLA2G4B (0.38) | LMNAPLA2G4BFFAR1PKMHTT | |
| SCHEMBL5315653 | 0.88 | LMNA (0.44) | LMNAFFAR1PKMHTTPGR | |
| SCHEMBL5315649 | 0.88 | LMNA (0.44) | LMNAFFAR1PKMHTTPGR | |
| SCHEMBL5335188 | 0.88 | FFAR1 (0.43) | LMNAPLA2G4BMAPK1L3MBTL1FFAR1 | |
| SCHEMBL5335192 | 0.88 | FFAR1 (0.43) | LMNAPLA2G4BMAPK1L3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |