SCHEMBL5315205

SCHEMBL5315205

CCCO/N=C(\COc1cc(CC(=O)O)cc(OCC)c1)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PLA2G4B P0C869 2/20 0.41
KMT2A Q03164 2/20 0.40
FABP1 P07148 3/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
AKR1C3 P42330 1/20 0.38
KDM4E B2RXH2 2/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
SRD5A2 P31213 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315206 1.00 FFAR1 (0.41) FFAR1LMNAMAPK1L3MBTL1PLA2G4B
SCHEMBL5314541 0.94 LMNA (0.41) FFAR1LMNAMAPK1L3MBTL1PLA2G4B
SCHEMBL5314547 0.94 LMNA (0.41) FFAR1LMNAMAPK1L3MBTL1PLA2G4B
SCHEMBL5335192 0.93 FFAR1 (0.43) FFAR1LMNAMAPK1L3MBTL1PLA2G4B
SCHEMBL5335188 0.93 FFAR1 (0.43) FFAR1LMNAMAPK1L3MBTL1PLA2G4B
SCHEMBL5309885 0.91 PLA2G4B (0.50) FFAR1LMNAPLA2G4BKMT2AFABP1
SCHEMBL5309894 0.91 PLA2G4B (0.50) FFAR1LMNAPLA2G4BKMT2AFABP1
SCHEMBL5312135 0.91 FFAR1 (0.41) FFAR1LMNAPLA2G4BKMT2AFABP1
SCHEMBL5312138 0.91 FFAR1 (0.41) FFAR1LMNAPLA2G4BKMT2AFABP1
SCHEMBL5315193 0.89 FFAR1 (0.44) FFAR1LMNAMAPK1L3MBTL1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007058504-A1 NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES, LTD. (KR) 2007-05-24 WO claimed
WO-2007058504-A1 NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES, LTD. (KR) 2007-05-24 WO disclosed