SCHEMBL5314635

SCHEMBL5314635

COC(=O)c1cc(O)cc(OS(C)(=O)=O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.61
CA2 P00918 6/20 0.61
CA12 O43570 5/20 0.61
CA7 P43166 5/20 0.61
CA9 Q16790 5/20 0.61
CA14 Q9ULX7 5/20 0.61
KDM4E B2RXH2 3/20 0.46
POLB P06746 2/20 0.46
XDH P47989 2/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
NFKB1 P19838 1/20 0.46
GFER P55789 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
FUT7 Q11130 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
STS P08842 1/20 0.42
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2893033 0.90 CA1 (0.48) CA1CA2CA12CA7CA9
SCHEMBL15720859 0.85 CA1 (0.47) CA1CA2CA12CA7CA9
SCHEMBL2900339 0.83 KDM4E (0.43) CA1CA2CA12CA7CA9
SCHEMBL732876 0.83 CA12 (0.56) CA1CA2CA12CA7CA9
SCHEMBL2892172 0.83 CA1 (0.40) CA1CA2CA12CA7CA9
SCHEMBL17653009 0.82 STS (0.45) CA1CA2CA12CA7CA9
SCHEMBL55814 0.80 CA1 (0.73) CA1CA2CA12CA7CA9
SCHEMBL23484294 0.80 ALDH1A1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL1146954 0.78 MEN1 (0.51) CA1CA2CA12CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL38869 0.78 CA1 (1.00) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007058504-A1 NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES, LTD. (KR) 2007-05-24 WO disclosed