SCHEMBL55814

SCHEMBL55814

COC(=O)c1cc(O)cc(OC)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.73
CA2 P00918 6/20 0.73
CA12 O43570 5/20 0.73
CA7 P43166 5/20 0.73
CA9 Q16790 5/20 0.73
CA14 Q9ULX7 5/20 0.73
KDM4E B2RXH2 3/20 0.53
XDH P47989 2/20 0.53
POLB P06746 2/20 0.53
GAA P10253 2/20 0.53
LMNA P02545 1/20 0.53
NFKB1 P19838 1/20 0.53
GFER P55789 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
FUT7 Q11130 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475746 0.87 CA1 (0.61) CA1CA2CA12CA7CA9
Methyl 3,5-Dimethoxybenzoate SCHEMBL204865 0.87 CA1 (0.61) CA1CA2CA12CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL38869 0.85 CA1 (1.00) CA1CA2CA12CA7CA9
SCHEMBL46504 0.85 CA12 (0.91) CA1CA2CA12CA7CA9
SCHEMBL2663326 0.85 CA1 (0.68) CA1CA2CA12CA7CA9
SCHEMBL20944289 0.83 CA1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL15516856 0.82 CA1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL713400 0.82 CA12 (0.63) CA1CA2CA12CA7CA9
SCHEMBL2657413 0.82 CA1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL709293 0.82 CA1 (0.63) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836059-A Process for the preparation of isoindolinone derivatives, novel intermediates used therein and process for the preparation thereof 忠北大学校产学协力团 2023-03-21 CN claimed
US-20230042112-A1 A Process For Preparing Isoindolinone Derivative, Novel Intermediates Used For The Process, And A Process For Preparing The Intermediates Chungbuk National University Industry-Academic Coopertion Foundation (KR) 2023-02-09 US claimed
EP-4073047-A1 A PROCESS FOR PREPARING ISOINDOLINONE DERIVATIVE, NOVEL INTERMEDIATES USED FOR THE PROCESS, AND A PROCESS FOR PREPARING THE INTERMEDIATES Chungbuk National University Industry-Academic Cooperation Foundation (KR) 2022-10-19 EP claimed
WO-2021112574-A1 A PROCESS FOR PREPARING ISOINDOLINONE DERIVATIVE, NOVEL INTERMEDIATES USED FOR THE PROCESS, AND A PROCESS FOR PREPARING THE INTERMEDIATES CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2021-06-10 WO claimed
US-12540123-B2 Process for preparing isoindolinone derivative, novel intermediates used for the process, and a process for preparing the intermediates CNG BIO CO., LTD. (KR) 2026-02-03 US disclosed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP disclosed
EP-4073047-B1 A PROCESS FOR PREPARING ISOINDOLINONE DERIVATIVE, NOVEL INTERMEDIATES USED FOR THE PROCESS, AND A PROCESS FOR PREPARING THE INTERMEDIATES CNG BIO CO LTD (KR) 2025-02-26 EP disclosed
CN-119118880-A F-18 marked PSMA inhibitor and preparation method and application thereof 四川大学华西医院 2024-12-13 CN disclosed
CN-115836059-B Method for producing isoindolinone derivative, novel intermediate used for the method, and method for producing the same 希恩巨生物有限公司 2024-11-08 CN disclosed
CN-114773249-B Compounds, pharmaceutical compositions and methods for treating inflammatory diseases 艾匹克治疗公司 2024-08-16 CN disclosed
US-20240262803-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS Chungdu Anticancer Bioscience Ltd (CN) 2024-08-08 US disclosed
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CHENGDU ANTICANCER BIOSCIENCE LTD (CN) 2024-07-18 US disclosed
EP-0934291-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-08-11 EP disclosed
EP-0934291-A4 SMITHKLINE BEECHAM CORP (US) 1999-08-11 EP disclosed
WO-1997016433-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1997-05-09 WO disclosed
EP-0351194-B1 Thiazole derivatives having a 5-lipoxygenase-inhibiting activity ICI PLC (GB) 1994-06-15 EP disclosed
US-5196422-A Antiinflammatory agents, antiallergens ICI PHARMA (FR) 1993-03-23 US disclosed
US-5089513-A Antiinflammatory agents; antiallergens; asthma; side effect reduction ICI PHARMA (FR) 1992-02-18 US disclosed
EP-0351194-A2 Thiazole derivatives having a 5-lipoxygenase-inhibiting activity IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-01-17 EP disclosed
US-4143055-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS GRUPPO LEPETIT S.P.A. (IT) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230042112-A1 A Process For Preparing Isoindolinone Derivative, Novel Intermediates Used For The Process, And A Process For Preparing The Intermediates DHPS, SDHA, SQLE CA1 3596/4885CA2 4226/4885CA12 4271/4885
US-20240262803-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CYP27A1, PNLIP, GOT2 CA1 1979/4885CA2 2447/4885CA12 532/4885
US-12540123-B2 Process for preparing isoindolinone derivative, novel intermediates used for the process, and a process for preparing the intermediates BDNF, APP, PSEN1 CA1 3477/4885CA2 4655/4885CA12 4680/4885
US-20240239806-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS CYP27A1, CPT1A, OAT CA1 1835/4885CA2 2310/4885CA12 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.