Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 7/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604964 | 0.85 | CYP19A1 (0.53) | ARCYP19A1ACLYBRD4MEN1 | |
| SCHEMBL2207835 | 0.81 | HPGD (0.53) | SLC40A1ACLYPOLBMEN1KMT2A | |
| SCHEMBL2204950 | 0.77 | SLC40A1 (0.46) | SLC40A1PTGES2ACLYKMT2A | |
| SCHEMBL14844725 | 0.76 | SLC40A1 (0.73) | SLC40A1ARCYP19A1PTGES2MCL1 | |
| SCHEMBL8752447 | 0.75 | CYP19A1 (0.69) | SLC40A1ARCYP19A1PTGES2ACLY | |
| SCHEMBL2209258 | 0.74 | FFAR4 (0.51) | SLC40A1POLB | |
| SCHEMBL2208959 | 0.73 | ALDH1A1 (0.50) | SLC40A1POLBMEN1KMT2A | |
| SCHEMBL183414 | 0.73 | MAPT (0.48) | TDP1 | |
| SCHEMBL2209302 | 0.73 | SLC40A1 (0.46) | SLC40A1MEN1KMT2A | |
| SCHEMBL2206279 | 0.73 | MEN1 (0.50) | SLC40A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341753-B1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-26 | — | — | EP | disclosed |
| EP-1341753-A1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002044139-A1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |